Feb 10, 2023
Neurotransmitter hypothesis: Most acceptable
Genetic factor
1. Positive symptoms of schizophrenia (or psychotic symptoms)
2. Negative symptoms of schizophrenia
3. Disorganisation symptoms
4. Motor symptoms (Catatonic symptoms/Symptoms of conation)
Treatment of Catatonia
Here’s a brief history of schizophrenia -
Important information
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Here are the positive and negative symptoms of schizophrenia -
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Important information
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Typical or first-Generation Antipsychotic | Atypical or second-Generation Antipsychotic | |
Mechanism | D2 antagonism | D2 and 5 HT2 antagonism |
Effective Against | Positive symptoms | Positive and negative symptoms (primarily active against positive symptoms) |
EPS | More Extrapyramidal side effects | Less extrapyramidal side effects (Not as strong blockers of dopamine receptors) |
Metabolic side Effect | Less metabolic side effects | More metabolic side effects (Weight gain, ↑blood sugar, Dyslipidemia) |
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