Sep 27, 2023
Children are most commonly affected by Wilms tumour, a rare kidney cancer. It is the most typical kidney cancer in children and is also referred to as nephroblastoma. Children between the ages of 3 and 4 are most frequently affected by Wilms tumours. Once a child reaches the age of 5, it is considerably less common, but it can still affect older children and even adults.
The one kidney is where Wilms tumours typically develop. However, it can occasionally occur simultaneously in both kidneys.
The prognosis for children with Wilms tumour has significantly improved over time because of advances in diagnosis and treatment of this condition. For the majority of children with Wilms tumours, the prognosis is favourable with treatment.
What causes Wilms's tumour is unknown.
Cancer starts when cells' DNA is altered. The instructions that inform cells what to do are encoded in their DNA. The adjustments instruct the cells to rapidly divide and expand. As part of their normal life cycle, healthy cells die, but cancer cells continue to exist. In the case of a Wilms tumour, the modifications result in additional kidney cells that eventually grow into a tumour.
Rarely, genetic mutations passed down from parents to children can increase the chance of Wilms tumour.
The signs and symptoms of a Wilms tumour can be extremely varied. Some children don't appear to be suffering any symptoms. However, some people with Wilms tumours experience one or more of the following symptoms:
Other signs could be:
There are several elements that could raise the likelihood of developing a Wilms tumour.
Children with certain birth problems, such as:
Wilms tumours can be a part of uncommon disorders, such as:
Wilms tumor can be diagnosed with the help of the following methods:
The healthcare provider may advise additional testing to determine whether the cancer has spread after identifying a Wilms tumour. If the cancer has progressed past the kidneys, a bone scan, chest CT scan, or X-ray can reveal this.
Choosing a course of treatment is influenced by the cancer's stage. The phases of Wilms tumour are as follows in the US:
Chemotherapy and surgery are frequently used in the treatment of Wilms tumours. Radiation therapy is occasionally a part of it. The type of treatment depends on the cancer's stage. A children's cancer centre that has experience treating this sort of cancer would be an excellent option given how rare it is.
Kidney removal may be the first step in the Wilms tumour treatment plan. Furthermore, surgery supports the diagnosis. To determine whether the tissue is carcinogenic and what form of cancer is present in the tumour, it is submitted to a lab after being removed during surgery.
Surgery options for a Wilms tumour include:
Chemotherapy uses strong drugs to attack cancer cells all over the body. When treating a Wilms tumour, numerous drugs are frequently used to kill cancer cells. A vein is used to inject the medicine.
Chemotherapy side effects vary depending on the drugs taken. Nausea, vomiting, lack of appetite, thinning hair, and an increased risk of infections are typical adverse effects. Inquire about potential side effects from your child's healthcare provider. Ask if the treatment may have caused any problems
Chemotherapy can decrease tumours and make them easier to remove when administered prior to surgery. It can eradicate any cancer cells that are still active in the body after surgery. Children with malignancies that have progressed too far may potentially be eligible for chemotherapy.
Chemotherapy is administered prior to surgery to children who have cancer in both kidneys. One kidney's potential survival may be increased as a result of this.
Radiation therapy may be administered to some children. High-powered energy beams are used in radiation therapy to destroy cancer cells. Protons, X-rays, and other kinds of energy can all contribute.
The child is positioned on a table for radiation treatment. Around the child, a large piece of equipment moves while shooting energy beams at the cancer. Nausea, diarrhoea, fatigue, and sunburn-like skin irritation are all potential adverse effects.
After surgery, radiation therapy may be given to some kids to eradicate any remaining cancer cells. Additionally, it might be applied to treat cancer that has spread to different parts of the body. Inquire if there might be long-term problems as a result of radiation therapy.
It is difficult to prevent Wilms tumour.
A medical professional could advise performing periodic renal ultrasounds to check for anything unusual in the kidneys if a child has any of the disorders that raise the risk of Wilms tumour. Wilms tumour cannot be prevented, but this screening might help in detecting the condition early.
Download the PrepLadder App and get the best neet pg online coaching with world-class video lectures, QBank, Mock Tests and more!
Download PrepLadder's best app for neet pg preparation for Android
Download PrepLadder's best app for neet pg preparation for ios
Get access to all the essential resources required to ace your medical exam Preparation. Stay updated with the latest news and developments in the medical exam, improve your Medical Exam preparation, and turn your dreams into a reality!
The most popular search terms used by aspirants