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Anti-Parkinsonian Therapy & Drug Options

Apr 14, 2023

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Parkinson’s Disease

Aim of Anti-Parkinsonian Therapy

Increase the level of Dopamine.


Levodopa (Pro-drug)

Drug Interaction L-Dopa

Contraindication of L-Dopa

Advantages of The Combination of Carbidopa With L-Dopa

Disadvantages of the Combination of Carbidopa With L-Dopa

MAO-B Inhibitor (Monoamine Oxidase)

Drugs Acting On MAO

Selegiline (Doprenyl)



COMT Inhibitors (Catechol Ortho Methyltransferase)

D2 Agonist

Ergot Derived

Non- Ergot derived.


Decreased ACH Level

Drugs ↓ Ach level is called Central anticholinergics.

Drugs Lowering Ach Level


Newer Drugs For Parkinson Disease

Anti-Parkinsonian Therapy Drug Options
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