Pharmacology Image Based Questions for NEET PG 2025

Q1. Which of the following statements regarding the dose-response curves for benzodiazepines and barbiturates is correct?

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1. ​Benzodiazepines demonstrate a steeper dose-response curve compared to barbiturates.
2. Benzodiazepines have a narrower therapeutic index compared to Barbiturates
3. Both benzodiazepines and barbiturates display a linear dose-response relationship.
4. Benzodiazepines and barbiturates show similar potency but differ in their maximal efficacy on the dose-response curve.

Ans. 1) Benzodiazepines demonstrate a steeper dose-response curve compared to barbiturates.​

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Q2. A 45-year-old patient with a history of epilepsy has been prescribed Valproate. Look at the following diagram depicting the GABA metabolic pathway. Which enzymes inhibited by Valproate are responsible for increasing GABA levels?

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1. ​GABA transaminase and Succinate semialdehyde dehydrogenase
2. GABA decarboxylase and Glutamate decarboxylase
3. GABA transaminase and Glutamate dehydrogenase
4. Glutamate decarboxylase and Succinate semialdehyde dehydrogenase

Ans. 1) GABA transaminase and Succinate semialdehyde dehydrogenase

Q3. A patient was diagnosed with Parkinson’s disease and started on drugs for the same 6 months ago. He now presents for a review with complaints of skin discolouration, as shown in the image below. Which of the following antiparkinson agents would have caused this presentation?

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1. Rasagiline
2. Trihexyphenidyl
3. Amantadine
4. Ropinirole

Ans. 3) Amantadine​

Q4. A 55-year-old patient who was diagnosed with schizophrenia and started on risperidone 4 months ago now presents with resting tremors, muscular rigidity in the upper limbs and reduced pace in movements. Which of the following is the most appropriate drug of choice for this patient ?

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1. Rasagiline
2. Bromocriptine
3. Amantadine
4. Benzhexol​

Ans. 4) Benzhexol

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Q5. A 42-year-old female with a 3-year history of worsening joint pain presented to the clinic with early morning stiffness and swelling in her wrists. Her symptoms were not relieved with ibuprofen. A physical examination of the hands is shown. What is the most appropriate first-line treatment for her condition?

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1. Hydroxychloroquine
2. Sulfasalazine
3. Methotrexate
4. Colchicine

​Ans. 3) Methotrexate

Q6. A 52-year-old female with a 10-year history of rheumatoid arthritis has been on certain drug therapy for the past 5 years. She recently underwent an ophthalmological examination, where the ophthalmologist noted the presence of the following condition. What is the maximum recommended daily dose of the drug (in mg/kg) that is considered safe to minimize the risk of developing this condition?

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1. 2.5 mg/kg
2. 5 mg/kg
3. 6.5 mg/kg
4. 10 mg/kg

​Ans. 2) 5 mg/kg

Q7. A patient presents with a fever and a red, tender, swollen left knee, which started two days ago. He was recently diagnosed with hypertension and started on hydrochlorothiazide. Immediate joint aspiration is done, and the microscopic picture is given below. Which of the following is the most appropriate initial management?

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1. Probenecid
2. Naproxen
3. Sulfinpyrazone
4. Febuxostat

Ans. 2) Naproxen

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Q8. A patient presents with left-sided chest pain, which started 5 hours ago, radiating to the left arm and doesn’t get relieved on taking rest. An ECG is taken immediately, which is given below. Which of the following is the drug for definitive management in this patient?

1. Nitroglycerin
2. Reteplase
3. Aspirin & ticagrelor
4. Morphine

Ans. 2) Reteplase

Q9. A 72-year-old female with a history of CHF presents to the emergency department with nausea, vomiting, and visual disturbances. Her ECG reveals a sinus bradycardia with PR interval prolongation, inverted T waves and a particular finding below. Laboratory investigations show elevated serum digoxin levels. Which of the following drugs should not be used in the treatment of drug toxicity for this patient?

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1. Nifedipine
2. Digibind
3. Lidocaine
4. KCL

 ​Ans. 1) Nifedipine

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Q10. A 42-year-old man is brought to the ED by his wife after fainting, with recent episodes of dizziness and palpitations.His history includes hypertension and atrial fibrillation, for which he was recently started on a new medication. His vital signs are blood pressure: 100/60 mmHg , heart rate: 140 bpm. An ECG is obtained and shows the following pattern:

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Based on the clinical presentation and the ECG, which of the following interventions is most appropriate for the initial management of this patient?

1. Administer intravenous amiodarone
2. Administer intravenous adenosine
3. Administer intravenous magnesium sulfate
4. Perform synchronised cardioversion 

Ans. 3) Administer intravenous magnesium sulfate

Q11. A patient in the emergency department presented with the following condition in ECG. Which of the following drugs is most suitable for rapidly controlling the ventricular rate in this situation?

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1. Metoprolol
2. Propranolol
3. Esmolol
4. Atenolol

​Ans. 3) Esmolol

Q12. Which of the following agents inhibits the action of an agonist on a receptor or the subsequent response but does not have any effect of its own?

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1. ​Drug A
2. Drug B
3. Drug C
4. Drug D

Ans. 3) Drug C

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Q13. In a pharmacology experiment, you observe that adding a competitive antagonist increases the EC50 without changing the maximum response. Adding a non-competitive antagonist decreases the maximum response without changing the EC50. Which of the following best describes the dose-response curve changes for these scenarios?

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1. Competitive antagonist shifts left, non-competitive antagonist shifts down.
2. The competitive antagonist shifts right, and the non-competitive antagonist shifts down.
3. The competitive antagonist shifts down, and the non-competitive antagonist shifts right.
4. Competitive antagonists shift right, non-competitive antagonists shift left.​​

Ans. 2) ​​The competitive antagonist shifts right, and the non-competitive antagonist shifts down.

Q14. A clinical trial of 4 new drugs was conducted, and the following graphs were obtained. Based on these graphs, which of the following statements is/are correct?

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a) Drug A has the highest efficacy as well as the highest potency.

b) Drug A has the highest efficacy but the lowest potency.

c) Drug D has the highest efficacy as well as the highest potency.

d) Drug B is more potent than drug C.

1. ​Statements a and d are correct
2. Statements b and d are correct
3. Only statement b is correct
4. None of the statements are correct

Ans. 2) Statements b and d are correct

Q15. A 55-year-old woman with a history of chronic constipation has been using over-the-counter laxatives for several months. During a routine colonoscopy, the gastroenterologist observes the following image. Which of the following is the implicated reason for this condition?

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1. Bisacodyl
2. Isabgol
3. Castor Oil
4. Senna

Ans. 4) Senna

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