Jun 05, 2020
Drug | Mechanism | Route | Indication |
Andexanet alpha | Bind to Factor Xa inhibitors | Intravenous | To reverse overdose of rivaroxaban and apixaban |
Brexanolone | GABA-A modulator | Intravenous | Post partum depression |
Baloxavirmarboxil | Inhibit viral replication by inhibiting Cap-dependent endonuclease activity of viral polymerase | Oral | Single dose treatment of Acute uncomplicated influenza |
Elagolix | GnRH antagonist | Oral | Pain associated with endometriosis |
Esketamine | Non-competitive NMDA antagonist | Intranasal | Treatment resistant depression |
Ibalizumab | MAb against CD4 | Intravenous | HIV |
Pretomanid | Inhibit mycolic acid synthesis | Oral | For XDR and MDR TB (in combination with bedaquiline and linezolid) |
Pitolisant | H3 antagonist/inverse agonist | Oral | Narcolepsy |
Tenapanor | Sodium hydrogen exchanger-3 (NHE-3) inhibitor | Oral | IBS with constipation |
Tafenoquine | Free radical mediated killing of hypnozoites | Oral | Single dose radical cure of P. vivax malaria |
Lemborexant | Dual Orexin Antagonist (DORA)- binds to both the orexin receptors OX1R and OX2R | Oral | Insomnia |
Remdesivir | Remdesivir triphosphate inhibits viral RNA dependent RNA polymerase | Intravenous | Coronavirus disease 2019 (COVID-19) |
Ubrogepant | CGRP receptor antagonist | Oral | Acute treatment of migraine with or without aura |
Rimegepant | CGRP receptor antagonist | Oral | Acute treatment of migraine with or without aura |
Lasmiditan | 5HT1F agonist | Oral | Acute treatment of migraine with or without aura |
Erenumab | Monoclonal antibody against CGRP receptor | SC | Migraine prophylaxis |
Galcanezumab | Monoclonal antibody against CGRP receptor | SC | Migraine prophylaxis |
Fremanezumab | Binds to CGRP ligand blocking its binding to CGRP receptor. | SC | Migraine prophylaxis |
Eptinezumab | Binds to CGRP ligand blocking its binding to CGRP receptor. | Intravenous | Migraine prophylaxis |
Romosozumab | MAB against sclerostin | SC | Osteoporosis in postmenopausal women at high risk of fracture |
A Content Creator with over five years of experience, Srishti is an expert at creating content related to several genres. She aims to make a difference through what she writes.
Loading...