High-Yield NEET SS Medicine General Medicine Questions

Preparing for the NEET SS exam can feel like navigating a maze, but fear not! We have got the perfect strategy to help you gauge your readiness by giving you a sneak peek into the exam format.

Dive into the NEET SS Medicine General Medicine Questions to gain insight into what to expect. Get started by practicing the questions below, boost your confidence and fine tune your NEET SS Medicine preparation.

1. A 23-year-old military recruit presents to the emergency department four days after a boot camp. He has been exercising vigorously in the heat, in uniform, and he has developed a rash on his neck, trunk, and thighs, which have been covered during his time out of doors. He notes he has been sweating heavily since he is not used to the heat. The rash is characterized by erythematous 2 to 4 mm papular and papulovesicular lesions. Which of the following is the first-line treatment for this patient's most likely diagnosis?

1. Salicylic acid, 1%
2. Oral antibiotics
3. Baby powder
4. Remove to cool environment and use topical antibiotics

2. A 23-year-old male skater is found after an avalanche in Shimla. He was buried under the snow for 5 minutes and it took his friends 3 hours to carry him to the base of the mountain. On exam, his fingers of the left hand are blistered and cold. What temperature is ideal for thawing frozen extremities?

1. 36-38°C
2. 37-39°C
3. 40-42°C
4. 42-44°C

3. An 80-year-old man with end-stage renal disease on hemodialysis has inoperable lung cancer with metastases to the liver. He cannot make medical decisions due to dementia. His children request a treatment that has been successfully used in early-stage lung cancer but has been demonstrated to offer no benefit in treating metastatic lung cancer. The patient’s family believes that "It's worth a try to prolong his life." Which of the following is the most appropriate course of action?

1. Inform the patient's family that the treatment will not be covered by insurance
2. Explain that you will not provide the treatment since it will not offer any benefit
3. Inform the patient's family that he has <6 months to live and treatment cannot be justified
4. Proceed with the treatment if it will not lead to patient harm

4. Immediately after a needle stick, a surgical first assist tests positive for HIV. Routine HIV screening nine months ago was negative. Over the past several months, he has performed invasive procedures on several patients and plans to continue this work. Is the surgical first assist required to share this information with their past and future patients?

1. Yes, all surgical patients should be aware if their surgeon has a potentially communicable disease
2. No, continue to use universal precautions; healthcare providers are not required to disclose their status to patients
3. Yes, inform your hospital and your patients of your HIV status
4. No, you are only required to inform your patients after you have been diagnosed with an AIDS-defining illness

5. A 6-month-old male presents with skin discoloration of the lower back. He has been growing and developing normally. Multiple family members, including both parents, had similar areas noted sometime in childhood. Physical examination reveals a 2.5 cm by 3.5 cm bluish-gray patch overlying the sacrum. Which of the following is the most appropriate next step?

1. No treatment
2. Laser therapy
3. Topical fluorinated steroids
4. Dermabrasion

6. A 9-year-old boy is brought to you in the ER following a bite to the face. He reportedly was playing roughly with a neighborhood dog when it bit him. He has no medical problems and his tetanus is up-to-date. His vitals in the ER are BP 90/50, HR 110, RR 20, Temp 98.9, Sat 99% on RA. Upon exam you see a deep 2 cm irregular laceration to the left cheek. There is no sensory deficit or muscle weakness. The mom is panicking and wants to know what can be done for her son's face. Your answer is:

1. Since this is a bite wound, suturing it is not advised because of the risk of infection. He needs amoxicillin/clavulanate for a week and the lac has to heal by secondary intention
2. This wound can be closed with skin adhesive following cleansing and antibiotic prophylaxis
3. Dog bites get infected less often than human and cat bites so local wound care is all that is needed to prevent infection
4. Since this is a cosmetically sensitive area, the wound can be sutured; however, thorough wound cleansing, antibiotic prophylaxis, and close follow-up are needed to minimize the chance of infection, and to address it if it does occur

7. A 55-year-old man slips and falls on his outstretched hand. He has a history of hypertension and diabetes. His vitals are T 37.2, HR 96, BP 129/84, O2 sat 99%. He denies head strike and neck pain. However, the patient has tenderness along the radial aspect of the left wrist and pain with axial loading of the thumb. This represents a possible fracture in which of the following bones?

1. Pisiform
2. Hook of the hamate
3. Ulnar styloid process
4. Scaphoid

8. A 16 year old male presents to the ER following a bicycle accident. He was jumping his bike at the skate park when he fell off onto his right arm. Radiology reports there is a closed transverse fracture of the radius and ulna. A closed transverse fracture has which of the following features?

1. A fracture at a right angle to the bone's axis, which has penetrated the skin
2. A fracture at a right angle to the bone's axis, which has not penetrated the skin
3. A fracture whose ends are driven into each other, and has not penetrated the skin
4. A fracture in which the break has a curved or sloped pattern, and has not penetrated the skin

9. An 8-year-old boy presents with wrist pain after a fall on his outstretched right hand. A radiograph of the injury is shown below. Which of the following is the most likely diagnosis? 

1. Salter-Harris I
2. Salter-Harris II
3. Salter-Harris III
4. Salter-Harris IV

10. A 28-year-old male with 5-year history of schizophrenia is brought to the ER unconscious by his parents . He is taking trifluoperazine. Examination reveals BP: 175/110, Temperature: 102 Fahrenheit, sweating, confusion, disorientation, and increased muscle tone. Lab results indicate a high white count, and impaired renal function. Which of the following is the best pharmacological intervention in this case?

1. Haloperidol
2. Propranolol
3. Bromocriptine
4. Lorazepam

11. A 37-year-old male with a diagnosis of schizoaffective disorder was discharged one week ago from the inpatient psychiatric unit on sertraline, risperidone, benztropine, and clonazepam. He presents to the emergency room today with a fever, tachycardia, flushed, dry skin, and clouded sensorium. His pupils are dilated. Labs are drawn but results are not yet available. You give the patient a trial of physostigmine, after which his symptoms temporarily improve. The most likely diagnosis is:

1. Neuroleptic malignant syndrome secondary to antipsychotic overdose
2. Anticholinergic delirium secondary to benztropine overdose
3. Serotonin syndrome secondary to sertraline
4. Malignant hyperthermia

12. Schizophrenia results in decreased life expectancy and is associated with cognitive and social disturbances that sharply limit capacity for true recovery and reintegration into the community. What is the factor that has the greatest influence on the course and outcome of schizophrenia?

1. Social and family stressors
2. Gender
3. Medication compliance
4. Premorbid functioning

Also Read: NEET SS Medicine: List of Important Topics

13. A 16-month-old boy is evaluated for a five-day history of bloody diarrhea. He has been drinking adequately, but today his diapers have been dry for the past 15 hours. On physical examination, he is irritable, pale, and tachycardic, with periorbital edema. A complete blood count reveals a hemoglobin level of 7 g/dL, and a platelet count of 95,000/mm³. A blood smear shows schistocytes. A serum BUN is 55 mg/dL, and the creatinine is 6 mg/dL. Urinalysis reveals gross hematuria. What is the probable etiology of his illness?

1. Group A Streptococcus
2. E. coli O157:H7
3. Staphylococcus aureus
4. Group B Streptococcus

14. A three-year-old girl is evaluated for abdominal pain, dysuria, and fever for 2 days. Physical examination is significant for suprapubic tenderness and apparent tenderness at the left costovertebral angle. Urinalysis reveals a urinary tract infection (UTI). This is the third UTI this patient has had. What is the indicated diagnostic procedure?

1. Voiding cystourethrogram
2. Nuclear renal scan
3. Cystoscopy
4. Intravenous pyelogram

15. A 19-year-old G1P0 female @ 17 weeks presents with generalized body pain. Her past medical history is concerning for sickle cell disease. She has not had an exacerbation in years but feels like this is consistent with the onset of her previous crises. Which of following statements is true regarding sickle cell disease in pregnancy?

1. Hydroxyurea is not recommended for use in pregnancy
2. Female fertility is often adversely affected due to sickle cell disease
3. Necessity for caesarean section decreases with sickle cell disease
4. Prophylactic transfusion is indicated for Hb <10 g/dL

16. A 32-year-old G2P1 female at 39 weeks presents to your small community hospital with concerns for impending delivery. After delivery of the head, you notice that it appears to retract towards the maternal perineum and delivery is arrested. Examination reveals that the fetal shoulders lie on a vertical axis. While waiting for the OB/GYN, what is the next most appropriate step?

1. Suprapubic pressure
2. Digital pressure on posterior shoulder
3. McRoberts maneuver
4. Episiotomy

17. Which of the following factors associated with longevity involves reduced calorie intake, increased survival, and affects nutrient sensing pathways?

1. Mitohormetics
2. Sirtuin activation
3. Rapamycin
4. Spermidine

18. Which of the following cognitive assessment tools is commonly used to assess various cognitive domains, including memory, attention, and language, in geriatric medicine?

1. MMSE (Mini-Mental State Examination)
2. MoCA (Montreal Cognitive Assessment
3. CAM (Confusion Assessment Model)
4. PHQ-9 (Patient Health Questionnaire-9)

19. A 6-year-old boy was seen in the acute care clinic due to a rash of two weeks duration, present at the hands, arms, trunk, and genitalia. It was intensely pruritic, especially at night. Two older siblings have a similar rash. The child was afebrile. Examination was normal except for assorted papules, vesicles and pustules, some in linear array (especially at the web spaces of the fingers) and some with excoriations, at the web spaces of the fingers, the palms, the soles, flexion creases of the elbows, the trunk and genitalia. Optimal treatment consists of antipruritics and which of the following?

1. Topical crotamiton
2. Topical lindane
3. Permethrin lotion 5%
4. Topical ivermectin

20. A 21 year old male present to the ER in an ambulance for altered mental status. The paramedics state that he was at an rave music show when his friends called the ambulance. He has been expressing repeated motions to the music according to his friends. On exam his vitals are BP 130/85 HR 128 RR 20 Temp 100.1 degrees Fahrenheit. Which of the following is a side effect of the most likely ingested substance?

1. Diarrhea
2. Bruxism
3. Pinpoint pupils
4. Lacrimation and runny nose

Hope you found this blog helpful for your NEET SS General Medicine preparation. For more informative and interesting posts like these, keep reading PrepLadder’s blogs.