Image Based Questions On Hematology

Diagnosis: Thalassemia 

Hepatosplenomegaly on per abdominal examination. Peripheral smear shows target cells. Image III shows typical physical appearance of the patient Chipmunk facies. Prominent cheek bones. Upturned nostrils · Prominent incisor teeth (lip is pulled outward).

Plasmacytoma

X ray skull shows lytic punched out lesions. · Presence of Mott cells: Due to accumulation of light chains in the cytoplasm · Presence of flame cell.

Macrocytic Anemia

Patient is having a combination of UMNL and Sensory involvement · Peripheral smear shows bigger RBCs: Macrocytic anemia · Image shows evidence of demyelination of spinal cord · All these are the presentation of Subacute Combined Demyelination(SACD) of the spinal cord · Miller Fischer syndrome presents with  Ophthalmoplegia, Ataxia , Arreflexia · Devic's disease is a variant of multiple sclerosis aka Neuromyelitis optica · Lead poisoning can be ruled out as there is no MCHC anemia.

Hand-Foot Syndrome

Hand foot syndrome is a condition because of sickling crisis · Black urine is a feature of PNH · Elevated Haptoglobin: Absence or decreased Haptoglobin levels are seen in hemolytic Anemia · Splenomegaly with gall stones; is a feature of hereditary spherocytosis.

Diagnosis: Thalassemia 

Multiple blood transfusions · X- ray skull is showing Hair-on end/ Crew cut appearance.

Hickman Catheter 

Image is showing porta catheter inserted just above the nipple named as Hickman catheter. Directly delivering drugs to large veins such as subclavian vein.

Non-Hodgkin's Lymphoma 

Hematological dissemination of cancer occurs to various organs.

Also Read: Basics of Neutrophils And Disorders of Neutrophils

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