Dec 30, 2022
Celine Dion has recently spoken about her battle with Stiff Person Syndrome (SPS), a rare neurological disorder. She was diagnosed in 2014 but had been dealing with its symptoms for much of her life.
The disease affects muscles, causing them to become highly stiff, leading to difficulty in moving. Unfortunately, there is no known cure yet for SPS. However, it can be managed with medication and physical therapy.
Stiff Person Syndrome is considered to be a rare disorder, with fewer than 1000 cases reported worldwide. The condition is more common in women than in men, and most cases are diagnosed in people over the age of 50.
Read this post to understand what this condition is all about. What are its symptoms, causes and treatment?
Stiff Person Syndrome (SPS) is a rare neurological disorder that causes progressive muscle stiffness and spasms in the body. It is characterized by frequent, painful and sudden muscle contractions that can make everyday activities difficult or even impossible.
This rare autoimmune neurological disorder initially affects the trunk and abdomen (the middle part of the body). Stiff Person Syndrome affects the muscles and nerves, resulting in muscle rigidity and spasms. The resulting pain and stiffness of the muscles can limit movement and cause posture to become rigid.
SPS is characterized by episodes of muscle stiffness and/or spasms that can be painful and disabling. The muscles can become stiff enough to cause difficulty walking or even standing.
The cause of SPS is unknown, but it is believed to be an autoimmune disorder in which the body's own antibodies attack certain parts of the central nervous system.
There are two main symptoms of stiff person syndrome:
In most cases, the trunk muscles are the first to become stiff. The rigidity causes pain and an aching discomfort.
It can involve the entire body or only a specific area and can last a few seconds, minutes or, occasionally, a few hours.
Spasms can be triggered by:
The exact cause of Stiff Person Syndrome is unknown, but research suggests that the condition is caused by an abnormal response of the body's immune system. Specifically, the body's own antibodies attack and damage neurons in the brain and spinal cord, which results in muscle stiffness and spasms. Environmental factors, such as infections or vaccinations, are believed to trigger this abnormal immune response.
In some cases, genetic factors might also play a role. Many people with SPS make antibodies against glutamic acid decarboxylase (GAD). GAD makes a neurotransmitter called gamma-aminobutyric acid (GABA), which helps control muscle movement. Although, it's important to note that the presence of GAD antibodies doesn't mean someone has SPS.
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