Must to Remember New Drugs for AIIMS Nov 2019

After sharing the complete list of New Drugs approved by the FDA in 2019, we have now up with a segregated list of important drugs. This list has been compiled by Dr. Gobind Rai Garg keeping in mind the upcoming AIIMS Nov exam.

DRUGS FOR AIIMS NOV 2019

The table includes the name of the drug, mechanism, route and indication.

Drug	Mechanism	Route	Indication
Afamelanotide	Melanocortin 1 receptor agonist	Subcutaneous	Phototoxicity in patients with erythropoietic protoporphyria
Andexanet alpha	Bind to Factor Xa inhibitors	Intravenous	To reverse overdose of rivaroxaban and apixaban
Apalutamide Darolutamide	Androgen receptor antagonist	Oral	Prostate carcinoma
Avatrombopag Lusutrombopag	Thrombopoietin receptor agonist	Oral	Thrombocytopenia in patients with chronic liver disease
Baloxavir marboxil	Inhibit viral replication by inhibiting Cap-dependent endonuclease activity of viral polymerase	Oral	Single dose treatment of Acute uncomplicated influenza
Baricitinib	Janus Kinase inhibitor	Oral	Rheumatoid Arthritis
Bremelanotide	Melanocortin receptor agonist	subcutaneous	Hypoactive sexual desire disorder in females
Brexanolone	GABA-A modulator	Intravenous	Post partum depression
Caplacizumab	vWF-directed antibody fragment	IV/SC	Thrombotic Thrombocytopenic Purpura
Elagolix	GnRH antagonist	Oral	Pain associated with endometriosis
Erenumab Fremanezumab Galcanezumab	Monoclonal antibody against CGRP	SC	Migraine prophylaxis
Esketamine	Non-competitive NMDA antagonist	Intranasal	Treatment resistant depression
Ibalizumab	MAb against CD4	IV	HIV
Inotersen	Antisense oligonucleotide against transthyretin mRNA	Subcutaneous	Polyneuropathy of hereditary transthyretin-mediated amyloidosis
Istradefylline	Adenosine A2 receptor antagonist	Oral	Off episode in Parkinsonism
Lasmiditan	5HT1F agonist	Oral	Acute severe migraine
Lofexidine	Alpha 2 agonist	Oral	To decrease opioid withdrawal symptoms
Megalastat	Pharmacological chaperone for Alpha galactosidase	Oral	Fabry’s disease
Moxidectin	Bind to Glutamate and GABA chloride channels	Oral	Onchocerciasis
Netarsudil + Latanoprost	Netarsudil: Rho kinase inhibitor Latanoprost: PGF2 apha	Topical	Open angle glaucoma
Patisiran	Small Interfering RNA based therapy against mutant transthyretin	Intravenous	Polyneuropathy in patients with transthyretin mediated amyloidosis
Pitolisant	H3 antagonist/inverse agonist	Oral	Narcolepsy
Pretomanid	Inhibit mycolic acid synthesis	Oral	For XDR and MDR TB (in combination with bedaquiline and linezolide)
Ravulizumab	C5 Complement inhibitor	Intravenous	Paroxysomal Nocturnal Hemoglobinuria
Romosozumab	MAb against sclerostin	Subcutaneous	Post-menopausal osteoporosis
Selinexor	Selective inhibitor of nuclear export	Oral	Multiple myeloma Diffuse large B cell lymphoma
Semaglutide	GLP-1 agonist	Oral	Type 2 diabetes mellitus
Solriamfetol	DA and NA reuptake inhibitor	Oral	For excessive day time sleepiness in Obstructive sleep apnea and Narcolepsy
Stiripentol	Increases GABAergic activity	Oral	Dravet Syndrome
Tafenoquine	Free radical mediated killing of hypnozooites	Oral	Single dose radical cure of P. vivax malaria
Tecovirimat	Inhibit formation of extracellular viral forms	Oral	Small pox
Tenapanor	NHE-3 inhibitor	Oral	IBS with constipation
Tolvaptan	Vasopressin V2 receptor antagonist	Oral	To slow kidney function decline in adult polycystic kidney disease

Also read our blogs on high-yield topics (subject-wise) for NEET PG 2024 Preparation:

NEET PG: High-Yield Topics for Pharmacology	NEET PG: High-Yield Topics For Radiology
NEET PG: High-Yield Topics For Pediatrics	NEET PG: High-Yield Topics for Surgery
NEET PG: High-Yield Topics for Ophthalmology	NEET PG: High-Yield Topics For Forensic Medicine
NEET PG: High-Yield Topics For PSM	List of All Medical PG Entrance Exams 2022-2023

We hope this list will surely prove helpful to you for the upcoming AIIMS exam.