Jul 31, 2023
Trisomy 18, also referred to as Edwards syndrome, is a highly significant genetic disorder that has an impact on how your child's body grows and develops. Trisomy 18 is characterized by various birth abnormalities, low birth weight, and peculiar physical characteristics.
Anyone can be afflicted by Edwards syndrome (trisomy 18). The unexpected and arbitrary appearance of an additional copy of chromosome 18 is one of the disease's hallmarks. With a mother's age upon conception, the likelihood of producing a kid with Edwards syndrome (trisomy 18) rises. It is extremely rare (less than 1%) to become pregnant again and have a second child after giving birth to a child with Edwards syndrome (trisomy 18).
Trisomy 18 (Edwards syndrome) is a condition in which there are three copies of chromosome 18 instead of the usual two.
There are 46 chromosomes in humans which are divided into 23 pairs. Your DNA, which serves as your body's handbook on how to form and function, is carried by chromosomes in your cells. Your parents each give you one set of chromosomes.
When cells form, they begin as a single fertilized cell in the reproductive organs (sperm in males and eggs in females). When cells divide (meiosis), they make copies of one another to form pairs. The duplicated cell has 23 chromosomes instead of 46, half as much DNA as the original cell, and a unique number for each pair of chromosomes.
When chromosomal pairs are meant to divide to produce eggs and sperm, there is a chance that they won't (perhaps because they are too sticky) and both copies will remain in the egg or sperm instead. These two copies combine with one from the other parent during fertilization to create a total of three copies. It is unpredictable and random, and it is not due to anything the parents did prior to or during pregnancy when there is an improper number of chromosomes.
A trisomy happens when a third copy of a cell joins a pair. Trisomy is short for "three bodies." When someone is diagnosed with Edwards syndrome, their cells contain a third copy of chromosome 18.
The babies with trisomy 18 frequently have a wide range of major health issues and physical flaws, including:
There are three main types of trisomy 18:
Despite the fact that an ultrasound during pregnancy is not a reliable method for identifying trisomy 18, a doctor may be wary about it. More precise methods, such as amniocentesis or chorionic villus sampling, analyze the chromosomes of cells collected from the amniotic fluid or placenta.
The doctor may postnatally suspect trisomy 18 based on the baby's face and body. It is feasible to check for chromosomal abnormalities in a blood sample. The chromosomal blood test can also be used to determine the risk that the mother will have another child with trisomy 18.
If you're concerned that an earlier pregnancy put your child at risk for trisomy 18 while they were still in the womb, speak with a genetic counselor.
Your healthcare practitioner will offer various tests to diagnose your unborn child if they exhibit trisomy 18 (Edwards syndrome) signs during pregnancy. Among these tests are:
Your baby's heart will be ultrasonically examined by your healthcare practitioner after birth to diagnose and treat any heart-related issues that may have arisen.
Frequently, the illness is so severe that newborns who survive are given comfort care. However, depending on the severity of their diagnosis, each kid with Edwards syndrome (trisomy 18) has a different course of treatment. Trisomy 18 or Edwards syndrome is incurable.
Trisomy 18 (Edwards syndrome) therapy may involve:
Support is available for you, your family, and your kid with Edwards syndrome (trisomy 18), particularly if you need assistance coping with the death of your child or navigating your child's challenging diagnosis.
There is no method to prevent Edwards syndrome (trisomy 18), which is the outcome of a genetic mutation. However, you can dramatically lower the possibility of having a kid with Edwards syndrome (trisomy 18) if you are eligible for preimplantation genetic testing in conjunction with in vitro fertilization. Speak with your healthcare practitioner about genetic testing if you intend to get pregnant and want to know your likelihood of giving birth to a child who has a genetic disorder.
Download the PrepLadder App and get the best neet pg online coaching with world-class video lectures, QBank, Mock Tests and more!
Download PrepLadder's best app for neet pg preparation for Android
Download PrepLadder's best app for neet pg preparation for ios
Get access to all the essential resources required to ace your medical exam Preparation. Stay updated with the latest news and developments in the medical exam, improve your Medical Exam preparation, and turn your dreams into a reality!
The most popular search terms used by aspirants