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High-Yield Topics for Pharmacology

May 15, 2023

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Subject Weightage 

Type of Questions asked in NEET?

High-Yield Topics For NEET PG in Pharmacology

NEET PG 2024 High Yield Topics for Pharmacology

To help make your NEET PG preparations more fruitful, PrepLadder has come up with a list of high-yield topics for pharmacology.

After carefully studying the exam pattern for the last 10 years and with the help of India's top Pharmacology faculty, Dr. Bharath Kumar VD, we have identified some must-read topics that will help you score better in the exam. Read on. 

Also read: NEET PG Preparation Tips That Will Guarantee A Good Rank


PrepLadder 6.0

Subject Weightage 

As per the latest pattern, the NEET PG exam is divided into three sections - A, B & C. Section A consists of 50 questions, Section B consists of 100 questions, and Section C consists of 150 questions. 

The marking scheme is the same throughout all the sections. Pharmacology is a part of Section B and comprises of 20 questions. So, the subject weightage in NEET PG 2024 for pharmacology is 80 marks.

Type of Questions asked in NEET?

Based on the latest exam pattern, the following are the primary types of questions that you can expect in the upcoming exam:

1. Single best answer

  • Case-based
  • Fact-based 
  • Concept-based
  • Numerical/Value-based

2. Image-based questions

3. True or false type questions

High-Yield Topics For NEET PG in Pharmacology

Pharmacology is an enormous and diverse subject but well-scoring nonetheless. Although you need to cover the entire syllabus once for your NEET-PG preparation, you must focus more on high-yield topics to make your learning more productive. Here are the most important topics for NEET PG 2024 -

Also Read: THE USE OF ARTIFICIAL INTELLIGENCE IN HEALTHCARE

Pharmacology Important Topics For NEET PG

Unit Name

Most Important Topics

General Pharmacology

  • Concept of Bioavailability - its clinical importance and how to calculate bioavailability 
  • First Pass Metabolism
  • PC-T Graph
  • Factors affecting volume of distribution
  • Routes of drug administration
  • Plasma protein binding
  • CYP substrates, inducers, inhibitors
  • Bioavailability and Dose response curve graphs
  • Drug antagonism types and examples
  • Competitive vs. non-Competitive antagonism
  • Drug schedules, essential medicines, FDC,TDM
  • First and zero-order kinetics
  • Phases of clinical trials(aim, participants and type of study)
  • Different types of receptors & which drugs act upon which receptors
  • Receptor location, second messenger and examples
  • Major teratogenic drug list
  • pk problems
  • Clinical Trials
  • Practicals including prescription 

ANS

  • Basic architecture and functions of the divisions of ANS
  • Uses of cholinergic drugs
  • Management of OP, Carbamate and atropine poisoning
  • Drugs acting at neuromuscular junction
  • Drugs used in myasthenia gravis and Alzheimer’s disease
  • Atropine and glycopyrrolate
  • Drugs used in bladder conditions (overactive bladder and BPH)
  • Adrenaline, noradrenaline and dopamine in detail
  • Receptors of the sympathetic and parasympathetic system
  • AChe inhibitors, including OP poisoning 
  • Uses of anticholinergic drugs and poisoning 
  • Used of adrenaline, noradrenaline, and dopamine
  • Beta-blockers (cardio selective vs. non-selective)
  • Contraindications of beta blockers
  • Prazosin uses and adverse effects
  • Anti-glaucoma drugs
  • Anti-obesity drugs

Autacoids

  • Difference between first and second-generation antihistamines
  • Drugs for Migraine (attack and prophylaxis) 
  • Antihistaminics (1st vs 2nd generation)
  • Antihistamine causing QT prolongation
  • Prostaglandin preparation and uses
  • Contraindications of Prostaglandin preparations
  • 5HT receptors
  • NSAIDs: PCM and aspirin in detail
  • Drugs for gout (acute vs. chronic)
  • Drugs for RA
  • DMARDs (mainly mechanism of action)

Renal Pharmacology

  • Mechanism and site of action of diuretics
  • Adverse effects of loop, thiazides and spironolactone
  • DOC in various edema conditions
  • Contraindications of mannitol
  • Tolvaptan
  • Uses of desmopressin and terlipressin

CVS

  • Difference between ACE inhibitors and ARBs
  • Reason for angioedema and dry cough with ACE inhibitors
  • Contraindications of ACE inhibitors
  • Drugs decreasing mortality in chronic CHF
  • Basic concepts and drugs in acute and chronic CHF
  • Digoxin in detail
  • Nesiritide
  • Nitrates mechanism of action in angina
  • Nitrates plus sildenafil
  • Calcium channel blockers( DHPs vs. Non DHPs)
  • Newer drugs in angina pectoris
  • First line antihypertensive drugs
  • Drugs used in hypertensive crisis
  • Antihypertensive drugs mechanism and major adverse effects
  • Antihypertensive drugs contraindicated in pregnancy
  • Drugs used in pulmonary hypertension
  • Classification of anti-arrhythmic
  • DOC for various arrhythmias
  • Amiodarone in details particularly adverse effects
  • Nitrates
  • New drugs for angina
  • Mechanism and names of anti-arrhythmic drugs
  • Statins and new anti-dyslipidemic drugs

Endocrine

  • Bromocriptine, cabergoline uses
  • Uses of octreotide
  • Drugs used in acromegaly
  • Uses of GnRH agonist and antagonist
  • Uterine relaxant and stimulants
  • Propylthiouracil and carbimazole difference
  • Insulin preparations
  • Metformin in detail
  • Anti-diabetic drugs-MOA, effect on glucose, weight and routes of administration
  • SGLT2 Inhibitors adverse effects
  • Teduglutide, Sotagliflozin, tirzepatide and saroglitazaar
  • Adverse effects and contraindications of corticosteroids
  • Steroids use in preterm labour and CAH
  • Drugs to treat Cushing disease
  • Bisphosphonates-MOA, USES and A/E
  • Bone forming and resorbing agents
  • Drugs used for BPH, Erectile dysfunction, premature ejaculation and prostate cancer 
  • SERM,SERD and aromatase inhibitors
  • Tamoxifen in detail
  • Mifepristone, clomiphene citrate
  • Osteoporosis

CNS

  • Difference between benzodiazepines and barbiturates
  • Management of benzodiazepines and barbiturates poisoning
  • Benzodiazepines safe in liver disease patient
  • Orexin antagonist and melatonin agonist
  • Types of seizures and DOC
  • Valproate, phenytoin, carbamazepine, topiramte and lamotrigene in details
  • Mechanism of action of anti-epileptic drugs
  • Drugs in alcohol, smoking and opioid de-addiction
  • Lithium in detail
  • Difference between typical and atypical antipsychotic
  • Adverse effects of typical antipsychotic, particularly extra-pyramidal symptoms and management
  • Clozapine, risperidone, aripiprazole in details
  • Drugs used in Parkinson’s, Alzheimer’s, Huntington’s and amyotrophic lateral sclerosis
  • Advantages and disadvantages of levodopa and carbidopa combination
  • SSRIs uses and adverse effects
  • Antidepressants causing sexual dysfunction
  • Morphine uses, contraindications and poisoning
  • Morphine vs. Pethidine
  • Tramadol and methadone specialty
  • Drugs used in neuropathic pain

Hematology

  • Warfarin and Heparin 
  • Basic mechanism of antiplatelet drugs
  • Newer oral anticoagulants

Drugs affecting blood and blood formation

  • Mechanism of action of anticoagulants, adverse effects, antidote and lab monitoring
  • Anticoagulants in pregnancy
  • NOACs/DOACs
  • Mechanism of action of antiplatelet drugs
  • Clopidogrel and CYP2C19
  • Management of acute and chronic iron overdose
  • Fibrinolytics and antifibrinolytics
  • Mechanism of action uses and adverse effects of statins, fibrates and Niacin

Respiratory System

  • Drugs used for prophylaxis and attack of asthma
  • MOA-Montelukast, omalizumab, cromoglycate
  • Bronchodilators
  • Adverse effects of salbutamol 
  • New drugs in asthma and COPD
  • Drugs used in Dry and productive cough
  • Bronchial Asthma
  • Peptic ulcer
  • Anti-emetic drugs

GIT

  • Metoclopramide and dystonia management
  • DOC for CINV, Morning sickness and motion sickness
  • PPIs – MOA and uses
  • H.pylori eradication regimen

Antimicrobials

  • Mechanism of action of antibacterial drugs
  • Major bacterial infection( DOC/First choice)
  • Anti-bacterial: cidal and static
  • Adverse effects of antibacterial drugs
  • Anti-bacterial safe in pregnancy, children and renal failure
  • Drugs used in STIs and prophylaxis
  • First line Anti TB drugs in detail(HRZE)
  • Bedaquiline in details
  • Second line TB drugs
  • Definition of MDR, pre XDR and XDR TB
  • Leprosy treatment regimen and management of lepra reaction
  • List of ineffective antimicrobials in certain infections
  • Metronidazole in detail
  • DOC for Helminthic infections
  • Mechanism of antifungals and DOC for systemic fungal infections
  • MOA of oseltamivir
  • Drugs used for COVID management
  • DOC for HSV, VZV,CMV, Hepatitis B and C
  • MOA and adverse effects of Anti HIV drugs
  • Treatment and prophylaxis of HIV and treatment of opportunistic infection in HIV patients
  • Malaria treatment and prophylaxis
  • Chloroquine, primaquine in detail

Anticancer and IS

  • Common adverse effects Anti-cancer drugs and the treatment/prevention of them
  • Mechanism of action of anticancer drugs
  • Cell cycle and non-cell cycle specific anticancer drugs
  • Cyclophosphamide, cisplatin, 5flurouracil, vincristine (in detail)
  • Methotrexate in detail
  • Small molecule inhibitors and Monoclonal antibodies in anticancer therapy
  • Immune check point inhibitors in anticancer therapy
  • Mechanism of action of immunosuppressant Drugs
  • Calcineurin inhibitors
  • Adverse effects of cyclosporine

Miscellaneous

  • Treatment of Hyperkalemia
  • Tricyclic antidepressants
  • Antidotes of various drugs

Download the FREE PDF featuring all the high-yield topics of Pharmacology and make sure nothing important from this vast subject is left out.

Make sure to cover all the topics mentioned above in detail, and you will be able to score excellent marks in the exam. Download the PrepLadder app now and be the first one to know the high-yield topics of the remaining 18 subjects. 

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