Nov 28, 2019
Drug | Mechanism | Route | Indication |
Andexanet alpha* | Bind to Factor Xa inhibitors | Intravenous | To reverse overdose of rivaroxaban and apixaban |
Apalutamide Darolutamide | Androgen receptor antagonist | Oral | Prostate carcinoma |
Avatrombopag Lusutrombopag | Thrombopoietin receptor agonist | Oral | Thrombocytopenia in patients with chronic liver disease |
Baloxavir marboxil* | Inhibit viral replication by inhibiting Cap-dependent endonuclease activity of viral polymerase | Oral | Single dose treatment of Acute uncomplicated influenza |
Baricitinib | Janus Kinase inhibitor | Oral | Rheumatoid Arthritis |
Brexanolone* | GABA-A modulator | Intravenous | Post partum depression |
Elagolix | GnRH antagonist | Oral | Pain associated with endometriosis |
Erenumab Fremanezumab Galcanezumab | Monoclonal antibody against CGRP | SC | Migraine prophylaxis |
Esketamine* | Non-competitive NMDA antagonist | Intranasal | Treatment resistant depression |
Ibalizumab* | MAb against CD4 | IV | HIV |
Lasmiditan* | 5HT1F agonist | Oral | Acute severe migraine |
Lofexidine | Alpha 2 agonist | Oral | To decrease opioid withdrawal symptoms |
Pitolisant | H3 antagonist/inverse agonist | Oral | Narcolepsy |
Pretomanid* | Inhibit mycolic acid synthesis | Oral | For XDR and MDR TB (in combination with bedaquiline and linezolide) |
Romosozumab* | MAb against sclerostin | Subcutaneous | Post-menopausal osteoporosis |
Semaglutide | GLP-1 agonist | Oral | Type 2 diabetes mellitus |
Stiripentol | Increases GABAergic activity | Oral | Dravet Syndrome |
Tafenoquine* | Free radical mediated killing of hypnozooites | Oral | Single dose radical cure of P. vivax malaria |
Tecovirimat | Inhibit formation of extracellular viral forms | Oral | Small pox |
Tenapanor | NHE-3 inhibitor | Oral | IBS with constipation |
Tolvaptan | Vasopressin V2 receptor antagonist | Oral | To slow kidney function decline in adult polycystic kidney disease |
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