Nov 28, 2019

| Drug | Mechanism | Route | Indication |
| Andexanet alpha* | Bind to Factor Xa inhibitors | Intravenous | To reverse overdose of rivaroxaban and apixaban |
| Apalutamide Darolutamide | Androgen receptor antagonist | Oral | Prostate carcinoma |
| Avatrombopag Lusutrombopag | Thrombopoietin receptor agonist | Oral | Thrombocytopenia in patients with chronic liver disease |
| Baloxavir marboxil* | Inhibit viral replication by inhibiting Cap-dependent endonuclease activity of viral polymerase | Oral | Single dose treatment of Acute uncomplicated influenza |
| Baricitinib | Janus Kinase inhibitor | Oral | Rheumatoid Arthritis |
| Brexanolone* | GABA-A modulator | Intravenous | Post partum depression |
| Elagolix | GnRH antagonist | Oral | Pain associated with endometriosis |
| Erenumab Fremanezumab Galcanezumab | Monoclonal antibody against CGRP | SC | Migraine prophylaxis |
| Esketamine* | Non-competitive NMDA antagonist | Intranasal | Treatment resistant depression |
| Ibalizumab* | MAb against CD4 | IV | HIV |
| Lasmiditan* | 5HT1F agonist | Oral | Acute severe migraine |
| Lofexidine | Alpha 2 agonist | Oral | To decrease opioid withdrawal symptoms |
| Pitolisant | H3 antagonist/inverse agonist | Oral | Narcolepsy |
| Pretomanid* | Inhibit mycolic acid synthesis | Oral | For XDR and MDR TB (in combination with bedaquiline and linezolide) |
| Romosozumab* | MAb against sclerostin | Subcutaneous | Post-menopausal osteoporosis |
| Semaglutide | GLP-1 agonist | Oral | Type 2 diabetes mellitus |
| Stiripentol | Increases GABAergic activity | Oral | Dravet Syndrome |
| Tafenoquine* | Free radical mediated killing of hypnozooites | Oral | Single dose radical cure of P. vivax malaria |
| Tecovirimat | Inhibit formation of extracellular viral forms | Oral | Small pox |
| Tenapanor | NHE-3 inhibitor | Oral | IBS with constipation |
| Tolvaptan | Vasopressin V2 receptor antagonist | Oral | To slow kidney function decline in adult polycystic kidney disease |

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