Sep 01, 2023
Takayasu's arteritis is an uncommon form of vasculitis, a group of illnesses that cause inflammation of the blood vessels. Takayasu's arteritis causes inflammation that damages the aorta, a large artery that links your heart to the rest of your body, as well as its major branches.
Arteries may develop blockages or restrictions as a result of the illness, or their walls may weaken and tear or bulge (aneurysm). It could also result in chest pain, arm pain, excessive blood pressure, and finally heart failure or a stroke.
If you don't have any symptoms, therapy might not be necessary. The majority of patients with the illness, however, need medications to manage arterial inflammation and prevent issues. Even with treatment, relapses are common, and your symptoms might change.
Takayasu's arteritis' initial inflammation has an unknown origin. Most likely, you have an autoimmune illness where your body mistakenly targets your own arteries. A virus or another infection may cause the sickness.
Takayasu's arteritis signs and symptoms frequently come in two stages.
Stage 1- During the first stage, you may experience:
These early warning signs and symptoms are not always present. Inflammation may harm your arteries for years before you notice anything is amiss.
Stage 2- As a result of the second stage's inflammation, your organs and tissues receive less blood, oxygen, and nutrients.
Stage 2 warning signs and symptoms could include:
Your doctor will ask you about your signs and symptoms, do a physical exam, and take your medical history. In order to help rule out other disorders that mimic Takayasu's arteritis and to solidify the diagnosis, he or she could also ask you to go through some of the following tests and treatments. Some of these tests could also be performed to monitor your treatment progress.
Your doctor can determine from the generated images if blood is flowing normally or if a blood vessel's stenosis is causing it to slow down or stop. Typically, Takayasu's arteritis patients have many stenosis-prone regions.
Takayasu's arteritis treatment focuses on reducing inflammation with medication and preventing future blood vessel damage. Because Takayasu's arteritis may still be active even after your symptoms become better, it can be challenging to treat. It's also possible that by the time you receive a diagnosis, irreparable harm has already been done.
On the other hand, if you don't have any symptoms, you might not need treatment or, if your doctor advises it, you might be able to taper and cease medication.
Also Read :
|Proctitis: Causes, Symptoms, Risk Factors, Diagnosis, Treatment, Prevention and Complications||Xerostomia (Dry Mouth): Causes, Symptoms, Diagnosis, Treatment and Complications|
|Ramsay Hunt Syndrome: Causes, Symptoms, Risk Factors, Diagnosis, Treatment, Prevention and Complications||The Wolff-Parkinson-White (WPW) Syndrome|
Discuss the medication(s) or medication combinations that you have available to you, as well as any potential adverse effects, with your doctor. Your physician might advise:
Corticosteroids are used to manage inflammation. A corticosteroid like prednisone (Prednisone Intensol, Rayos) is typically the first course of treatment for such conditions. You might need to take the medication for a long time even if you start to feel better. When you achieve the lowest amount required to reduce inflammation, your doctor may start progressively lowering the dose. Your doctor might eventually advise you to stop using the drug altogether.
Weight gain, an increased risk of infection, and thinning bones are all potential side effects of corticosteroids. Your physician could advise taking a calcium supplement and taking vitamin D to help prevent bone loss.
Other medicines that weaken the immune system. Your doctor may prescribe medications like methotrexate (Trexall, Xatmep, among others), azathioprine (Azasan, Imuran), and leflunomide (Arava) if your illness doesn't react well to corticosteroids or if you experience problems as the dose of your medicine is dropped. Mycophenolate mofetil (CellCept), a drug designed for organ transplant recipients, has a positive response in certain patients. An elevated risk of infection is the most frequent adverse effect.
Immune system-regulating drugs. Your doctor might recommend medications that address immune system abnormalities (biologics) if you don't react to conventional treatments, but more study is required. Etanercept (Enbrel), infliximab (Remicade), and tocilizumab (Actemra) are some examples of biologics.
An increased risk of infection is one of these medications' most frequent side effects.
You may require surgery to open or bypass any significantly restricted or clogged arteries in order to maintain a continuous blood flow. This frequently helps to alleviate specific symptoms like chest pain and high blood pressure. But occasionally, the narrowing or blockage may return, necessitating a second surgery.
Additionally, surgery can be required if you develop large aneurysms in order to stop them from rupturing. They consist of:
Cycles of inflammation and healing in the arteries may cause one or more of the problems mentioned below in people with Takayasu's arteritis:
Download the PrepLadder App and get the best neet pg online coaching with world-class video lectures, QBank, Mock Tests and more!
Download PrepLadder's best app for neet pg preparation for Android
Download PrepLadder's best app for neet pg preparation for ios
Get access to all the essential resources required to ace your medical exam Preparation. Stay updated with the latest news and developments in the medical exam, improve your Medical Exam preparation, and turn your dreams into a reality!
The most popular search terms used by aspirants