Fibromyalgia- Causes And Treatment
May 16, 2024

Diffuse pain throughout the body, including the joints, muscles, and spine, without any obvious signs of inflammation at these locations is the clinical syndrome.
Clinical Features
Most typical attribute: Sharp pain that radiates down the spine and affects the muscles, joints, soft tissues, and many painful areas. The symptoms that are linked to it include fatigue, irritable bowel syndrome, non-restorative sleep, neuropsychiatric signs, and predominant diarrhea.
Chronic Fatigue Syndrome Vs Fibromyalgia
Features Chronic fatigue syndrome Fibromyalgia Predominant symptom Fatigue Pain Occurrence More often abrupt Not abrupt Cause History of antecedent viral infection No history of viral infection ESR and CRP Raised Not much raised compared with CFS
Etiology of Fibromyalgia
The precise cause of the condition is unknown. Abnormalities in the descending nociceptive pathway include: Increased glutamate and substance P; Decreased serotonin and norepinephrine; Reduced pain threshold. Reduced HPA axis reactivity to stress o Low cortisol levels. In cases of chronic fatigue syndrome, substance P is normal.
Also Read: Reactive Arthritis- Etiology, Diagnosis And Treatment
Diagnosis of Fibromyalgia
There are 18 sensitivity sites on the body; if 11 of the 18 points are positive, fibromyalgia is assumed; pressure applied Tenderness: 4 kg; pressing on the designated locations with the thumb. The nail bud is branching; this suggests that 4 kg of pressure is being applied.

Also Read: Antiphospholipid Syndrome (APS)
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ACR 2016 Criteria
All the 4 criteria should be met. 75% members with chronic fatigue Syndrome will also have fibromyalgia.
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Criteria |
Description |
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Criteria 1 |
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Criteria 2 |
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Criteria 3 |
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Criteria 4 |
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| Widespread pain index image | Maximum possible score: 19 Minimum possible score: 1 Patients is filling based on the pain during the past 7 days WPI score ≥7, SSC ≥5 WPI score 4 to 6, SSC ≥9 |
| Symptom severity score image | Range 0 to 12 It include: Fatigue Weakening unrefreshed (Non restorative sleep) Cognitive symptoms: Fibro Fog Description of blurriness Other symptoms: Headache Abdominal pain Depression |
Management of Fibromyalgia
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Pharmacological treatment |
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Non pharmacological treatment |
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Also Read: Aortic Aneurysm- Thoracic And Abdominal Aortic Aneurysm
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Clinical Features
Chronic Fatigue Syndrome Vs Fibromyalgia
Etiology of Fibromyalgia
Diagnosis of Fibromyalgia
ACR 2016 Criteria
Management of Fibromyalgia
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