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Progeria-Hutchinson-Gilford Progeria Syndrome (HGPS)- Pathogenesis, Clinical Features and Treatment

Oct 19, 2023

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Etiopathogenesis of Progeria

WHAT CAUSES PROGERIA?

Farnesylation Process

METHYLATED FARNESYL GROUP

CLINICAL FEATURES OF PROGERIA

1. DERMATOLOGICAL MANIFESTATIONS

FAILURE TO THRIVE

2. OCULAR ABNORMALITIES

3. CRANIOFACIAL AND DENTAL ABNORMALITIES

4. BONY AND CARTILAGINOUS ABNORMALITIES

5. HEARING ABNORMALITIES

6. SEXUAL DEVELOPMENT

7. CVS INVOLVEMENT

CAUSES OF DEATH

INVESTIGATIONAL FINDINGS IN PROGERIA

Progeria-Hutchinson-Gilford Progeria Syndrome (HGPS)- Pathogenesis, Clinical Features and Treatment
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