Last 5 Years PYQ's in Anesthesia for NEET PG
Jan 8, 2025

If you are a NEET PG aspirant, you must have seen that Anesthesia is a high-scoring yet tricky subject to conquer. There is no way better to do that than practicing past-year questions. You can determine past year trends, spot exam’s favourite questions, and sharpen your clinical knowledge by revisiting the last five years’ PYQs.
And, the best part is that we have made it super easy for you. In this blog, we have compiled a list of must-know Anesthesia PYQs with detailed explanations. And, we can assure you that these questions will help you strengthen your concepts and boost your confidence. Without further ado, let’s go through these questions and make sure you’re exam ready.
Download FREE PDFs of Last 5-Year NEET PG PYQs – All Subjects
Q1. A patient presented with headache, vomiting, and fever. Meningitis was suspected. While performing a lumbar puncture, which is the last structure you will pierce just before entering the lumbar cistern?
- Ligamentum flavum
- Dura mater
- Arachnoid membrane
- Pia mater
Ans. 3) Arachnoid membrane
Explanation:
While entering the lumbar cistern, the last structure you puncture is the arachnoid membrane. This is because it is the innermost layer.
Also read: Drugs included in Local Anaesthetics
Q2. A young male patient was given a regional block with 0.25% bupropion for a minor surgical procedure. Shortly after the injection, the patient suddenly became unresponsive and the pulse was not recordable. Which of the following would be the best course of management for this patient?
- CPR with 20% intralipid
- CPR with sodium bicarbonate
- CPR with dobutamine
- CPR with calcium
Ans. 1) CPR with 20% intralipid
Explanation:
The symptoms exhibited by the patient are of local anesthesia systemic toxicity, LAST, which is best treated with CPR with 20% intralipid.
Q3. What is the specific action being demonstrated in the provided image?
- Head tilt, chin lift
- Jaw thrust
- Head extension
- In-line manual stabilisation
Ans. 1) Head tilt, chin lift
Explanation:

In this image, the maneuvers being performed are head tilt and chin tilt, where the patient's head is inclined backward and the chin is tilted upwards.
Also read: Regional Anesthesia: Types, Instruments and Side Effects
Q4. Identify the mask in the image used for patients with COVID-19 infection.
- Venturi mask
- Hudson mask
- Nebuliser
- Non-rebreathing mask
Ans. 4) Non-Rebreathing Mask
Explanation:
- The Non-Rebreathing Mask (NRB) is a type of oxygen mask frequently used in medical settings to provide high oxygen concentration to the patient.
- This mask provides the highest concentration of oxygen at a flow rate of 6 to 15 liters/min.
- It is sometimes called a demand oxygen mask or a partial non-rebreather mask. The NRB mask consists of a face mask that covers the patient's mouth and nose, connected to an oxygen reservoir bag.
- The patient can breathe in pure oxygen because of the reservoir bag, which boosts the amount of oxygen in the bloodstream and facilitates better breathing. Therefore, the mask used for patients with COVID-19 infection is the non-rebreathing mask.

Q5. What is the mechanism of action of the curare group of muscle relaxants?
- Persistently depolarizing at neuromuscular junction
- Competitively blocking the binding of ACh to its receptors
- Repetitive stimulation of ACh receptors on muscle endplate
- Inhibiting the calcium channels on presynaptic membrane
Ans. 2) Competitively blocking the binding of ACh to its receptors
Explanation:
These drugs competitively bind to the nicotinic acetylcholine receptors at the neuromuscular junction, preventing the binding of acetylcholine (ACh) and thereby inhibiting muscle contraction.
Also read: Categories of Oxygen Therapy: Low-Flow vs High-Flow Systems
Q6. Which of the following intravenous anesthetics does not result in myocardial depression?
- Etomidate
- Propofol
- Thiopentone
- Ketamine
Ans. 1) Etomidate
Explanation:
Etomidate: No effect on BP Cardiac output or coronary perfusion
Q7. Which of the following is not used for induction of anesthesia in pediatric patients?
- Halothane
- Sevoflurane
- Desflurane
- Nitrous oxide
Ans. 3) Desflurane
Explanation:
- Desflurane is not commonly used for the induction of anesthesia in pediatric patients.
- It is mainly used for the maintenance of anesthesia due to its pungent odor and potential airway irritation during induction
Also read: OPIOIDS: Classification, Pharmacokinetics
Q8. Which of the following agents does not elicit pain on injection?
- Ketamine
- Propofol
- Etomidate
- Thiopentone
Ans. 1) Ketamine
Explanation:
Ketamine is known for its unique pharmacological properties, including its analgesic effects. It has a less painful injection compared to other intravenous agents.
Q9. When do you put a victim in the following position?

- Conscious patient with pulse & breathing present.
- Unconscious patient with pulse & breathing present.
- Unconscious patient with pulse present but no breathing.
- Unconscious patient without pulse but breathing present.
Ans. 2) Unconscious patient with pulse and breathing present
Explanation:
The given image shows the recovery position and is used for an unconscious patient who is breathing and has a pulse. This position helps keep the airway open and allows any fluids to drain, reducing the risk of airway obstruction.
Also read: Intravenous Anesthetic Agents: Opioids, Non-Opioids
Q10. What is the typical pressure setting for the valve in a Mapleson circuit?
- 10-20 mmHg
- 30-40 mmHg
- 10-20 cm H2O
- 30-40 cm H2O
Ans. 4) 30-40 cm H2O
Explanation:
- The typical pressure setting for the adjustable pressure-limiting (APL) valve in a Mapleson circuit is 30-40 cm H2O.
Q11. A 25-year-old patient undergoing orthopedic surgery who underwent general anesthesia suddenly developed a rise in EtCO2, temperature, and also muscle rigidity. Which of the following drugs leads to such complications?
- Propofol
- Nitrous oxide
- Etomidate
- Halothane
Ans. 4) Halothane
Explanation:
- The scenario describes malignant hyperthermia, a life-threatening reaction to certain anesthetic agents, including halothane. It is characterized by increased EtCO2, hyperthermia, and muscle rigidity.
Also read: Cholinergic Drugs (Sympathetic & Parasympathetic system)
Q12. In the given capnograph, what does the marked area denote?

- Expiratory upstroke
- Alveolar Plateau
- Inspiratory downstroke
- Inspiratory baseline
Ans. 2) Alveolar Plateau
Explanation:
In a normal capnograph, the marked area represents the alveolar plateau phase. This is the flat part of the capnograph, indicating constant exhalation of CO2.
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