May 19, 2023
Problems in IDM
Long Term Problems
Neonatal hypoglycemia is defined when the plasma glucose level is less than 30 mg/dL in the first 24 hours of life and less than 45 mg/dL (2.5 mmol/L) thereafter. Neurologic damage including mental retardation, recurrent seizure activity, developmental delay, and personality abnormalities are some of the most severe long-term effects.
IV 10% dextrose @ 2ml/kg stat bolus
Continuous IV fluids (@ GIR of 6 mg/kg/min)
Monitor blood glucoses and titrate GIR according to
Blood Glucose value (GIR= glucose infusion
Complications and congenital malformations are more in babies born to mothers with pre-existing diabetes than those with GDM.
Pederson's Maternal Hyperglycemia/ Fetal
Hyperplasia and hypertrophy of fetal pancreatic beta cells
Fetal hyperinsulinemia → Neonatal Hypoglycemia
Insulin acts as a Growth Factor for Fetus
Extra Medullary Hematopoiesis
RDS in Infants
Macrosomia/ Large for Date Baby
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