May 22, 2017
Many students come up to us with queries about what to study and what not to study in Pharmacology for PG entrance examination. Pharmacology is a very diverse as well as very scoring subject, to get your desired PG seat you should have a good command on this subject and no topic should be left completely. However, there are some mandatory topics that must be revised in the final few days. The table below comprise of the list of all the “Must Know” and “Desirable to Know” topics you must go through before the exam.
IMPORTANT TOPICS IN PHARMACOLOGY |
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TOPIC | MUST KNOW | DESIRABLE TO KNOW | |
GENERAL | pH, pKa, ionizationBioavailability First pass metabolism Vd PPB Prodrugs CYP substrates, inducers, inhibitors Metabolic reactions Formulas | First and zero order kineticsTDM Receptors types and examples DRC Pharmacogenetics Clinical trials Drug labels Orphan drugs Essential drugs | Enzyme inhibition (competitive, non-competitive and uncompetitive)Types of antagonists Pharmacovigilance Evidence based medicine |
ANS | AChE inhibitorsOP Poisoning Sympathetic receptors location | Catecholamines tableBeta blockers Anticholinergics | Alpha blockersGlaucoma Rabbit practicals |
AUTACOIDS | AntihistaminicsPCM and aspirin poisoning | DMARDsGout Migraine | PG actionsOther NSAIDs |
CVS | DigoxinNew drugs for CHF Drugs decreasing mortality in CHF | JNC 8 guidelines for hypertensionNew antianginal drugs Statins | Pulmonary hypertensionAntiarrhythmics New hypolipidemic drugs |
KIDNEY | K sparing diuretics | - | Free water clearanceVasopressin antagonists |
ENDOCRINE | SomatostatinGnRH agonist and antagonist New antidiabetic drugs | OsteoporosisSERM OCPs Mifepristone | Antithyroid drugsOral hypoglycemic agents Adverse effect of steroids SPRM Anti-androgens |
CNS | Short acting BZDParkinsonism Multiple sclerosis Antiepileptic drugs | Antipsychotic names and adverse effectsSSRI and SNRI TCA poisoning Lithium and mania | Newer hypnotic drugsMAO inhibitors Opioids |
ANAESTHESIA | Local anaesthetics mechanism and special pointsSCh and NDMRs MAC and Bld gas partition coefficient | Colour coding of cylindersPin index system Xenon Halothane Ketamine | Spinal anaesthesiaNeurolept analgesia |
HEMATOLOGY | Anticoagulants specially new | AntiplateletsFibrinolytics | Iron deficiency anemiaGrowth factors |
RESPIRATORY | Bronchodilators | DOC for different asthma types | Theophylline |
GIT | Peptic ulcer | Crohn’s and Ulcerative colitis | Metaclopramide, domperidone IBS |
ANTIMICROBIALS | Important points (Review of Pharmacology 11th edition/page:380-382)Tuberculosis with RNTCP Malaria | Mechanism of drug resistanceBeta lactams Aminoglycosides Fluoroquinolones HIV Hepatitis C | TetracyclinesMacrolides Cotrimoxazole Leprosy Antifungal |
ANTICANCER | CCS and Non-specific drugsGeneral and specific adverse effects of anticancer drugs (Specially chemo-man cartoon) | Monoclonal antibodiesTyrosine kinase inhibitors Newer anticancer drugs | - |
IMMUNOLOGY | CyclosporineTacrolimus | Monoclonal antibodiesThalidomide | - |
SPECIAL TOPICS | New drugs approved in last 12 months (uses only)Anti-obesity drugs | Erectile dysfunctionAnti-smoking drugs Treatment of HIT Treatment of hyperkalemia | - |
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