Pathology is a very important subject of MBBS. 40-50 direct or indirect questions appear from pathology in PG entrance exams.
A majority of the candidates find this subject tough and challenging. Keeping the candidates’ concern in mind, we have compiled this article that will cast light on the most important topics of Pathology for Medical PG entrance.
When in doubt you must refer to latest edition of Robbins’ Pathology since it has been written keeping in mind South-East Asia.
Most Important Topics of Pathology for Medical PG Entrance
I. Cell as a Unit of Health & DiseaseImportant topics
Cell Genome- In this, you need to prepare Epigenetics and how to diagnose a case of Epigenetics.
Types of Collagen, where they are located and the diseases which occur due to their deficiency.
Stem cells
II. Cell Adaptation, Repair and Injury
This chapter is very important and must not be missed.
Important Topics
Reversible Injury
Irreversible Injury
Difference between Reversible & Irreversible Injury
Factors which lead to increased vascular permeability (Regularly repeated)
Cellular events of Inflammation
Mediators of Inflammation
Cell Repair and the day-wise approach
IV. GeneticsImportant Topics
Mendelian Inheritance – Autosomal Dominant & Autosomal Recessive. Be cautious of the fact that all dominant diseases do not present like autosomal recessive.
Factors affecting autosomal dominant diseases such as Co-dominance, Pleiotropism, etc.
Examples of Automosal Dominant and Autosomal Recessive
Non-Mendelian Inheritance such as Trinucleotide Repeat and Silencing
Genomic Imprinting, Maternal and Paternal Disomy
Neoplasia – Try to remember only the most important mutations.
Metaplasia, dysplasia, anaplasia
Cell cycle
Oncogenes
Cell cycle inhibitors
Ras, proto-oncogenes
Tumor suppressor genes
Paraneoplastic syndromes
Lab diagnosis of cancer
Tumor markers
Tumor suppressor Genes - Prepare the ones present in the Nucleus
Warbug effect
Tumor markers used in Diagnostic and Prognostic field nowadays
V. Immunity
If you prepare Immunity from Pathology, there is no need to prepare Immunity from Microbiology.
Important Topics
NK cells, Dendritic Cells and Antigen preventing cells
Amyloidosis is very very important
VI. Haematology
There are 3 units in this – RBCs, WBCs and Coagulation
Important Topics of WBC
ALL
CLL
DLBCL
Burkitts
AML – in particular reference to the new WHO 2008 Classifications
CML is very important topic and must not be missed
Sicle Cell Anaemia - Mutations and the factors which increase or decrease Sickling
Thallasemia – Peripheral Smear finding
Iron Deficiency Anaemia – Prepare the difference between Iron Deficiency Anaemia and Anaemia of Chronic Disease
Differential diagnosis of Pancytopenia – Pancytopenia with cellular bone marrow and Pancytopenia with Acellular Bone Marrow.
Important Topics of Coagulation
Primary hemostatic plug
Secondary hemostatic plug
Deficiency of Coagulation Factors
Von Willebrand disease
DIC
VII. Systemic Pathology
This topic can be covered with Medicine.
Important Cancers
Lung Cancers
Endothyroid Carcinoma.
Mesothelioma and the Histological Difference between Mesothelioma and Adenocarcinoma
Thyroid Carcinoma – Types
RCC
CNS Tumors
Other Important topics
Kidney
Casts
Different types of nephritis (Membranous, Minimal Change disease)
Focal Segmental glomerulosclerosis.
Liver
Alcoholic liver disease.
Non Alcoholic liver disease.
NASH (Non Alcoholic Steatohepatitis)
NAFLS (Non Alcoholic Fatty Liver Disease)
CNS
Schwannoma
Medulloblastoma
Astrocytoma
Also read: How to study all 19 subjects for NEET PGSICKLE CELL ANEMIA AND THALASSEMIA - NEET PG Pathology
We are sure that this article will definitely acquaint the aspirants with the most important topics of Pathology for Medical PG Entrance.
Prepare the Aforesaid topics to Excel in Pathology in Medical PG entrance.
Stay Tuned for the latest updates on Medical PG preparation!
Best Wishes.
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