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Sickle Cell Anemia And Thalassemia - NEET PG Pathology 

Apr 11, 2023

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1. Sickle Cell Anemia

Factors of Sickle Cell Anemia 


Compound Heterozygous


Clinical Features of Sickle Cell Anemia 

Other Crisis of Sickle Cell Anemia

Diagnosis of Sickle Cell Anemia

Sickle-shaped cells

a. Sickling Test

Sickling test

b. Solubility Test

c. Hemoglobin Electrophoresis

d. HPLC: High-Pressure Liquid Chromatography.

HPLC graph

Treatment of Sickle Cell Anemia 

2. Thalassemia


A. β Thalassemia

β Thalassemia - Genetics

a. Pathogenesis of β Thalassemia Major

Peripheral Smear Finding of β Thalassemia Major

b. β Thalassemia Minor/Trait

Nestroft Test

Method of Nestroft Test

B. α Thalassemia

Golf ball inclusions

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